HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 117600615, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | HCID 117600148 | HCID 117600148 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 117600615 | HCID 117600615 | — |
Reaction Steps
A solution of reactant 4-Bromo-2-(methylamino-phenyl-methyl)-phenylamine (3.4 g, 12 mmol) in THF (150 mL) is added triphosgene (3.81 g, 13 mmol). After the addition the mixture is stirred at r.t. for 3 h. Then H2O is added and is extacd with EtOAc, dried over Na2SO4 and concentrated. The residue is purified by chromatography on silica gel to give product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199988B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-d2409f95c47d462cbfcdc6a9a592762b |
| Source note | uspto-grants-2015_12 |