HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 59966803, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | Boc-2-Abz-OH | HCID 4087778 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | HCID 59966803 | HCID 59966803 | — |
Reaction Steps
To the stirred solution of 2-tert-Butoxycarbonylamino-benzoic acid in acetonitrile (20 ml) is added N,O-hydroxylaminehydrochloride, EDC.HCl (1.520 g, 7.929 mmol), HOBT (1.300 g, 8.497 mmol) and triethylamine (2.500 g, 24.752 mmol) is stirred at room temperature for 40 mins. The progress of the reaction is monitored by TLC (30% EtOAc/Hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199988B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-c94972cd641244708f461b097b1c64aa |
| Source note | uspto-grants-2015_12 |