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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497755Generated: October 26, 2026

4-(5-Tributylstannanyl-pyrazol-1-yl)-benzonitrile → 4-{5-[2,7-Dimethyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrile

https://huagongshe.com/reaction/1497755

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(5-Tributylstannanyl-pyrazol-1-yl)-benzonitrileHCID 86708088—
Reactant6-Bromo-2,7-dimethyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridineHCID 86708093—
Product4-{5-[2,7-Dimethyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrileHCID 73051125—

Reaction Steps

The title compound was prepared from 6-bromo-2,7-dimethyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridine (Int. 7, 100 mg, 0.27 mmol) and 4-(5-tributylstannanyl-pyrazol-1-yl)-benzonitrile (Int. 3, 186 mg, 0.405 mmol) using a similar method to that used in Example 1 (Step 4) (91 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199984B2
Source datasetuspto-grants-2015_12
ORD IDord-b58440e18100426dbc2ebb28f7e7ac6c
Source noteuspto-grants-2015_12