HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-Tributylstannanyl-pyrazol-1-yl)-benzonitrile → 4-{5-[7-Methyl-8-(3-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-Tributylstannanyl-pyrazol-1-yl)-benzonitrile | HCID 86708088 | — |
| Reactant | 6-Bromo-7-methyl-8-(3-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine | HCID 86708095 | — |
| Product | 4-{5-[7-Methyl-8-(3-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrile | HCID 73051127 | — |
Reaction Steps
The title compound was prepared from 6-bromo-7-methyl-8-(3-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridine (Int. 9, 30 mg, 0.085 mmol) and 4-(5-tributylstannanyl-pyrazol-1-yl)-benzonitrile (Int. 3, 62 mg, 0.135 mmol) using a similar method to that used in Example 1 (Step 4) (28 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09199984B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-b153a80367244d5ebf00e78787a88f98 |
| Source note | uspto-grants-2015_12 |