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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1497787Generated: October 25, 2026

4-{5-[2-Amino-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrile → HCID 86708105, compound

https://huagongshe.com/reaction/1497787

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-{5-[2-Amino-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrileHCID 73050976—
Reactant5-Bromo-2-chloro-4-methyl-3-(3-trifluoromethyl-phenyl)-pyridineHCID 86708100—
ProductHCID 86708105HCID 86708105—

Reaction Steps

The title compound was prepared from 4-{5-[2-amino-7-methyl-8-(3-trifluoromethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-pyrazol-1-yl}-benzonitrile (Ex. 1, 100 mg, 0.22 mmol) using a similar method to that used for Intermediate 14 (73 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199984B2
Source datasetuspto-grants-2015_12
ORD IDord-2608d25f9d034766bca68172b7e69942
Source noteuspto-grants-2015_12