HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,4-Dichloropyrimidine → 5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,4-Dichloropyrimidine | HCID 77531 | — |
| Edukt | (4-Fluoro-3-formylphenyl)boronic acid | HCID 2778651 | — |
| Produkt | 5-(2-Chloro-pyrimidin-4-yl)-2-fluoro-benzaldehyde | HCID 24901981 | 40% |
Reaktionsschritte
2,4 dichloropyrimidine and 4-fluoro-3-formylphenylboronic acid was coupled following procedure A. The yield was 40%. LC-MS showed the product was >95% pure and had the expected M+H+ of 237.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07732444B2 |
| Quelldatensatz | uspto-grants-2010_06 |
| ORD ID | ord-d4bfd07c48a945799be086e5695c723b |
| Quellennotiz | uspto-grants-2010_06 |