Dimethyl Sulfoxide → 4-{4-Chloro-2-[2-(cyclobutyloxy)pyridin-4-yl]phenoxy}-3-cyano-N-(2,4-dimethoxybenzyl)-N-1,2,4-thiadiazol-5-ylbenzenesulfonamide
Reaction equation
[C:20](=[O:21])([O-:22])[O-:23].[C:26](#[N:27])[c:28]1[cH:29][c:30]([S:35](=[O:36])(=[O:37])[N:38]([c:39]2[n:40][cH:41][n:42][s:43]2)[CH2:44][c:45]2[c:46]([O:53][CH3:54])[cH:47][c:48]([O:51][CH3:52])[cH:49][cH:50]2)[cH:31][cH:32][c:33]1[F:34].[CH3:55][S:56]([CH3:57])=[O:58].[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([O:15][CH:16]3[CH2:17][CH2:18][CH2:19]3)[n:12][cH:13][cH:14]2)[c:5]([OH:8])[cH:6][cH:7]1.[K+:24].[K+:25]>>[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[cH:10][c:11]([O:15][CH:16]3[CH2:17][CH2:18][CH2:19]3)[n:12][cH:13][cH:14]2)[c:5]([O:8][c:33]2[c:28]([C:26]#[N:27])[cH:29][c:30]([S:35](=[O:36])(=[O:37])[N:38]([c:39]3[n:40][cH:41][n:42][s:43]3)[CH2:44][c:45]3[c:46]([O:53][CH3:54])[cH:47][c:48]([O:51][CH3:52])[cH:49][cH:50]3)[cH:31][cH:32]2)[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4e668846791b427592d1bf069152421f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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