N-Aminophthalimide → HCID 77531930, compound

HRID 1498918Notes

Reaction equation

HRID 1498918 reaction equation
[NH2:1][N:2]1[C:6](=[O:7])[C:5]2=[CH:8][CH:9]=[CH:10][CH:11]=[C:4]2[C:3]1=[O:12].[CH3:13][O:14][C:15]1[CH:22]=[CH:21][C:18]([CH:19]=O)=[CH:17][C:16]=1[CH3:23]>C(O)C>[CH3:13][O:14][C:15]1[CH:22]=[CH:21][C:18]([CH:19]=[N:1][N:2]2[C:3](=[O:12])[C:4]3[C:5](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]2=[O:7])=[CH:17][C:16]=1[CH3:23]

Participants

4

Reactant 2

HCID 74645N-AminophthalimideHCID 1229363-Methyl-4-anisaldehyde

Product 1

HCID 77531930HCID 77531930, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

N-aminophthalimide (1.62 g) and 4-methoxy-3-methylbenzaldehyde (1.50 g) were added to ethanol (20 ml), the mixture was stirred under heat reflux overnight. The mixture was allowed to cool to a room temperature, and then the precipitate was separated by filtration, washed with ethanol, and dried under a reduced pressure to give the title compound (2.50 g, 84%).

Workup

  1. temperatureunder heat
  2. temperaturereflux overnight
  3. customthe precipitate was separated by filtration
  4. washwashed with ethanol
  5. customdried under a reduced pressure

Sources & evidence

ORD record
ord-f6cb0f907222423eb5720bae70aba808
Source dataset
uspto-grants-2015_12
Patent number
US09200008B2

Reaction notes

Loading…