Ethyl 5-phenyl-1,3,4-oxadiazole-2-carboxylate → 1-[2-Fluoro-4-({1-[(5-phenyl-1,3,4-oxadiazol-2-yl)carbonyl]azetidin-3-yl}oxy)benzyl]-4-methylpiperazine

HRID 149898Notes

Reaction equation

HRID 149898 reaction equation
[NH:1]1[CH2:2][CH:3]([O:5][c:6]2[cH:7][c:8]([F:20])[c:9]([CH2:10][N:11]3[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH2:16]3)[cH:18][cH:19]2)[CH2:4]1.[c:21]1(-[c:27]2[n:28][n:29][c:30]([C:32](=[O:33])[O:34][CH2:35][CH3:36])[o:31]2)[cH:22][cH:23][cH:24][cH:25][cH:26]1>>[N:1]1([C:32]([c:30]2[n:29][n:28][c:27](-[c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[o:31]2)=[O:33])[CH2:2][CH:3]([O:5][c:6]2[cH:7][c:8]([F:20])[c:9]([CH2:10][N:11]3[CH2:12][CH2:13][N:14]([CH3:17])[CH2:15][CH2:16]3)[cH:18][cH:19]2)[CH2:4]1

Participants

3

Reactant 2

HCID 651752Ethyl 5-phenyl-1,3,4-oxadiazole-2-carboxylateHCID 666534801-(4-(Azetidin-3-yloxy)-2-fluorobenzyl)-4-methylpiperazine

Product 1

HCID 565979901-[2-Fluoro-4-({1-[(5-phenyl-1,3,4-oxadiazol-2-yl)carbonyl]azetidin-3-yl}oxy)benzyl]-4-methylpiperazine

Sources & evidence

ORD record
ord-3327ba78918a4ee2812e045aa650febf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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