反应详情

To a solution of 4 (64 mg, 0.27 mmol) in dry methanol (10 mL) was added morpholine (55 μL, 0.62 mmol) dropwise, and the resulting reaction was stirred for 2 h at rt. The resulting precipitate was then filtered, washed with water and then a mixture of 5:1 methanol/water, and the remaining solid was dried in vacuo to furnish 5 (50 mg, 0.17 mmol, 64%) as a white solid.

1. customthe resulting reaction
2. filtrationThe resulting precipitate was then filtered
3. washwashed with water
4. additiona mixture of 5:1 methanol/water
5. customthe remaining solid was dried in vacuo