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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1499174Generated: October 31, 2026

Lithium Hydroxide → HCID 117947790, compound

https://huagongshe.com/reaction/1499174

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant(S)-ethyl 8-(2-amino-6-((R)-1-(5-ethyl-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-3-carboxylateHCID 131734246—
ProductHCID 117947790HCID 117947790—

Reaction Steps

Hydrolysis of (S)-ethyl 8-(2-amino-6-((R)-1-(5-ethyl-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane-3-carboxylate using the LiOH general method provided the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199994B2
Source datasetuspto-grants-2015_12
ORD IDord-9b2ae38c44514b8eb5e36cf730c1fbdd
Source noteuspto-grants-2015_12