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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1499268Generated: November 2, 2026

Lithium Hydroxide → CID 117951917

https://huagongshe.com/reaction/1499268

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactantmethyl 9-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-3,9-diazaspiro[5.5]undecane-2-carboxylateHCID 117942117—
ProductCID 117951917HCID 117951917—

Reaction Steps

Hydrolysis of methyl 9-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)-3,9-diazaspiro[5.5]undecane-2-carboxylate using the LiOH general method provides the title compound as an off-white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09199994B2
Source datasetuspto-grants-2015_12
ORD IDord-f18c8a9237a84c1388b88c59be0fc2eb
Source noteuspto-grants-2015_12