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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 149978Generated: October 26, 2026

Dichloromethane → 7-[1-(Pyridin-4-yl)piperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/149978

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
ReactantTert-butyl 7-hydroxy-1,2,3,4-tetrahydroisoquinoline-2-carboxylateHCID 10562576—
Reactant(1-(Pyridin-4-YL)piperidin-4-YL)methanolHCID 11310048—
Product7-[1-(Pyridin-4-yl)piperidin-4-ylmethoxy]-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl esterHCID 11281679—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-cfe99d45dcac4f4e9a30d1edc69675fc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)