Formaldehyde → HCID 86677746, compound

HRID 1499824Notes

Reaction equation

HRID 1499824 reaction equation
Cl.Cl.[Cl:3][C:4]1[C:5]([CH3:31])=[C:6]([CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[C:7]([O:23][CH3:24])=[C:8]([CH:10]([N:12]2[C:16]3=[N:17][CH:18]=[N:19][C:20]([NH2:21])=[C:15]3[C:14]([CH3:22])=[N:13]2)[CH3:11])[CH:9]=1.[CH2:32]=O>>[Cl:3][C:4]1[C:5]([CH3:31])=[C:6]([CH:25]2[CH2:26][CH2:27][N:28]([CH3:32])[CH2:29][CH2:30]2)[C:7]([O:23][CH3:24])=[C:8]([CH:10]([N:12]2[C:16]3=[N:17][CH:18]=[N:19][C:20]([NH2:21])=[C:15]3[C:14]([CH3:22])=[N:13]2)[CH3:11])[CH:9]=1

Participants

3

Reactant 2

HCID 712FormaldehydeHCID 86677747HCID 86677747, compound

Product 1

HCID 86677746HCID 86677746, compound

Procedure

This compound was prepared according to the procedure of Example 139 step 7, using of 1-[1-(5-chloro-2-methoxy-4-methyl-3-piperidin-4-ylphenyl)ethyl]-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine dihydrochloride and formaldehyde as the starting materials. The product was isolated as a racemic mixture. LCMS calculated for C22H30ClN6O (M+H)+: m/z=429.2; Found: 429.1.

Workup

  1. customThis compound was prepared
  2. customThe product was isolated as a racemic mixture

Sources & evidence

ORD record
ord-50dbef3131a440619d65e15a415d5e60
Source dataset
uspto-grants-2015_12
Patent number
US09199982B2

Reaction notes

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