2,4-Dichloro-6-phenylpyrimidine → HCID 86702708, compound

HRID 1499984Notes

Reaction equation

HRID 1499984 reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[CH:5]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]=1.[C:15]([C:17]1[CH:18]=[C:19](B(O)O)[CH:20]=[CH:21][CH:22]=1)#[N:16]>>[Cl:1][C:2]1[N:7]=[C:6]([C:21]2[CH:20]=[CH:19][CH:18]=[C:17]([C:15]#[N:16])[CH:22]=2)[CH:5]=[C:4]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]=1

Participants

3

Reactant 2

HCID 2415542,4-Dichloro-6-phenylpyrimidine2×HCID 27343253-Cyanophenylboronic acid

Product 1

HCID 86702708HCID 86702708, compound

Procedure

2-chloro-4-(3-cyanophenyl)-6-phenylpyrimidine was synthesized by the same method as in syntheses of 2,4-dichloro-6-phenylpyrimidine in the above (4-1-1), except that 2,4-dichloro-6-phenylpyrimidine was used in place of 2,4,6-trichloropyrimidine and that 3-cyanophenylboronic acid was used in place of phenylboronic acid.

Sources & evidence

ORD record
ord-a0102c39dd4b4071b4cecfbc2aa728bb
Source dataset
uspto-grants-2015_12
Patent number
US09203043B2

Reaction notes

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