反应详情

Acetyl L-carnitine (35.3 g) was weighted and put in a flask (250 ml), into which 80 ml ethanol was added. The mixture was heated to dissolve completely. An ethanol solution containing 31.0 g arsenic acid was slowly and dropwise added into the solution of acetyl L-carnitine, continued to stir for a further 1 h after the addition, cooled to room temperature, and white crystals were precipitated. After grinding, 64.4 g of white powder was obtained. Yield: 97.1%. Melting temperature: 150.6° C.-152.1° C. 1H-NMR (DMSO, 500 MHz), δ 2.28 (m, 2H), 3.16 (m, 9H), 3.35 (m, 2H), 4.36 (m, 1H), 9.51 (s, 3H); IR: 3423 cm−1, 2975 cm−1, 2399 cm−1, 1723 cm−1, 1477 cm−1, 1302 cm−1, 1191 cm−1, 1106 cm−1, 879 cm−1, 769 cm−1.

1. customput in a flask
2. temperatureThe mixture was heated
3. dissolutionto dissolve completely
4. additionafter the addition
5. customwhite crystals were precipitated
6. customAfter grinding