Methyl iodide → HCID 3026785, compound

Participants

Reaction Steps

Dimethyl-m-tolyl-amine (556 mg, 4.12 mmol) was dissolved in dry dichloroethane (2 mL) and methyl iodide (880 mg, 6.2 mmol) was added dropwise. The reaction was refluxed for 1 h during which time sedimentation occurred. The reaction was cooled to room temperature, the solid filtered out, washed with dichloromethane, and dried overnight in a desiccator to give a white powder (809 mg, 72% yield). 1H NMR (DMSO-d6): δ7.82 (s, 1H), 7.74 (d, J=8.5 Hz, 1H), 7.51 (t, J=8 Hz, 1H), 7.93 J=7.5 Hz, 1H), 3.59 (s, 9H), 2.42 (s, 3H); MS (ESI, m/z): 150 (M+).

Provenance & Evidence