Hydroxide → HCID 117953245, compound

HRID 1500131Notes

Reaction equation

[I-].[CH3:2][N+:3]1([CH3:12])[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[CH:9]([CH3:11])[CH3:10].[OH-:13]>>[OH-:13].[CH3:2][N+:3]1([CH3:12])[CH2:8][CH2:7][CH2:6][CH2:5][CH:4]1[CH:9]([CH3:10])[CH3:11]

Participants

Reactant 2

HCID 961Hydroxide

HCID 117953359HCID 117953359, compound

Product 1

HCID 117953245HCID 117953245, compound

Procedure

N,N-dimethyl-2-isopropylpiperidinium cation was synthesized in the manner as described in Example 1 starting with 2-isopropylpiperidine, potassium bicarbonate and methyl iodide in methanol as the reagents. The reaction afforded N,N-dimethyl-2-isopropylpiperidinium iodide in greater than 95% yield. The iodide counter-ion was ion exchanged for hydroxide in the manner as described in Example 1 to afford the corresponding N,N-dimethyl-2-isopropylpiperidinium hydroxide in quantitative yield.

Sources & evidence

ORD record: ord-351cfae177864f7d9ef544d5320ab935
Source dataset: uspto-grants-2015_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09206052B2

Reaction notes

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