Butanal → HCID 86714715, compound

Participants

Reaction Conditions

Reaction Steps

Butanal (68 mL, 0.75 mol) was added dropwise over 20 minutes to a solution of diisobutylamine (87 mL, 0.50 mol) in toluene (100 mL) at room temperature under a nitrogen atmosphere. After installation of a Dean-Stark tube, the mixture was warmed to 130° C. and refluxed. 50 mL of distillate containing water was extracted twice. The reaction mixture was cooled to room temperature and then distilled under reduced pressure (0.25 mmHg, 51-55° C.) to obtain the title compound (67.67 g, yield: 74%) as a colorless oil substance.

Provenance & Evidence