2,2-Dichloro-N-[(1S,2R)-1-fluoromethyl-2-hydroxy-2-(4-trimethylstannanyl-phenyl)-ethyl]-acetamide → HCID 73603574, compound

Participants

Reaction Steps

Following the general procedure of step 3, Example 4 and using the product of step 2, Example 4 and making non-critical variations but using the product of step 1, Example 23, the title compound is obtained (85 mg): 1H NMR (300 MHz, DMSO-d6) δ 1.61 (d, 3H), 4.25 (m, 1.5H), 4.40-4.60 (m, 2H), 4.70 (m, 0.5H), 4.91 (m, 1H), 5.99 (d, 1H), 6.53 (s, 1H), 7.48 (d, 2H), 7.55 (d, 1H), 7.70 (d, 2H), 8.13 (dd, 1H), 8.62 (bd, 1H), 8.89 (m, 1H). MS (ESI+) m/z 410 [M+H].

Provenance & Evidence