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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1500462Generated: November 1, 2026

HCID 86718001, compound → 5-Methyl-2,3-dihydro-1-benzofuran-7-amine

https://huagongshe.com/reaction/1500462

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86718001HCID 86718001—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
Product5-Methyl-2,3-dihydro-1-benzofuran-7-amineHCID 55284828—

Reaction Steps

A mixture of 5-methyl-7-nitro-2,3-dihydrobenzofuran (1c) (0.30 g, 1.7 mmol) and Pd/C (150 mg, 50%) in THF (5 mL) was introduced H2. It was stirred at ambient temperature for 12 h. The mixture was filtered through celite and concentrated to give the title compound (1d) as a solid. MS-ESI (m/z): 150 (M+1)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09206166B2
Source datasetuspto-grants-2015_12
ORD IDord-f941dcdf87b0401590f439875f967338
Source noteuspto-grants-2015_12