HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86718001, compound → 5-Methyl-2,3-dihydro-1-benzofuran-7-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86718001 | HCID 86718001 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 5-Methyl-2,3-dihydro-1-benzofuran-7-amine | HCID 55284828 | — |
Reaction Steps
A mixture of 5-methyl-7-nitro-2,3-dihydrobenzofuran (1c) (0.30 g, 1.7 mmol) and Pd/C (150 mg, 50%) in THF (5 mL) was introduced H2. It was stirred at ambient temperature for 12 h. The mixture was filtered through celite and concentrated to give the title compound (1d) as a solid. MS-ESI (m/z): 150 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09206166B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-f941dcdf87b0401590f439875f967338 |
| Source note | uspto-grants-2015_12 |