m-Chloroperbenzoic acid → HCID 86718021, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-allyl-4-methyl-6-nitrophenol (7b) (0.50 g, 2.5 mmol) and m-CPBA (0.64 g, 2.5 mmol) in CHCl3 (9 mL) was stirred for 6 h at 85° C. The mixture was poured into saturated NaHSO3 (20 mL), extracted with DCM (40 mL), washed with brine, dried and concentrated. The residue was purified by column chromatography on silica gel eluting with hexanes/EtOAc (10:1) to give the title compound (7c) as a solid. MS-ESI (m/z): 210 (M+1)+.

Provenance & Evidence