HCID 178502444, compound → HCID 178502443, compound

Participants

Reaction Steps

A solution of (S)-4-[1-(5-Chloro-4′-{2-[(2S,4S)-1-((S)-2-methoxycarbonylamino-3-methyl-butyryl)-4-methyl-pyrrolidin-2-yl]-1H-imidazol-4-yl}-2-trifluoromethoxy-biphenyl-4-ylcarbamoyl)-piperidin-4-yl]-3-methyl-piperazine-1-carboxylic acid tert-butyl ester 2 TFA (6.35 mg, 0.006 mmol; Preparation 24) in 4.0 M HCl in 1,4-dioxane (0.1 mL) was stirred at RT for 30 min and concentrated under vacuum to provide the title intermediate. (m/z): [M+H]+ calcd for C39H50ClF3N8O5 803.35 found 803.8.

Provenance & Evidence