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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1500848Generated: November 3, 2026

5-Chloro-2-(chloromethyl)-1-[3-(methylsulfonyl)propyl]-1H-benzimidazole → 5-chloro-2-{[3-(ethylsulfonyl)-1H-indol-1-yl]methyl}-1-[3-(methylsulfonyl)propyl]-1H-benzimidazole

https://huagongshe.com/reaction/1500848

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-2-(chloromethyl)-1-[3-(methylsulfonyl)propyl]-1H-benzimidazoleHCID 61808180—
Reactant3-(Ethylsulfonyl)-1h-indoleHCID 89924470—
Product5-chloro-2-{[3-(ethylsulfonyl)-1H-indol-1-yl]methyl}-1-[3-(methylsulfonyl)propyl]-1H-benzimidazoleHCID 72949975—

Reaction Steps

Example 1-5 was prepared in analogy to Example 1-2 by using 3-ethanesulfonyl-1H-indole and 5-chloro-2-(chloromethyl)-1-(3-(methylsulfonyl)propyl)-1H-benzo[d]imidazole instead of 3-(methylsulfonyl)-1H-indole and 5-chloro-2-(chloromethyl)-1-(3-(methylsulfonyl)propyl)-1H-benzo[d]imidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09206191B2
Source datasetuspto-grants-2015_12
ORD IDord-f938059c7ecc4d7490cc2cb5afe3ec1f
Source noteuspto-grants-2015_12