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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1500849Generated: October 30, 2026

3-(isopropylsulfonyl)-1H-indole → 5-Chloro-1-[3-(methylsulfonyl)propyl]-2-{[3-(propan-2-ylsulfonyl)-1H-indol-1-yl]methyl}-1H-benzimidazole

https://huagongshe.com/reaction/1500849

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(isopropylsulfonyl)-1H-indoleHCID 58342279—
Reactant5-Chloro-2-(chloromethyl)-1-[3-(methylsulfonyl)propyl]-1H-benzimidazoleHCID 61808180—
Product5-Chloro-1-[3-(methylsulfonyl)propyl]-2-{[3-(propan-2-ylsulfonyl)-1H-indol-1-yl]methyl}-1H-benzimidazoleHCID 72950141—

Reaction Steps

The title compound was prepared in analogy to Example 1-2 by using 5-chloro-2-(chloromethyl)-1-(3-(methylsulfonyl)propyl)-1H-benzo[d]imidazole and 3-(isopropylsulfonyl)-1H-indole instead of 3-(methylsulfonyl)-1H-indole and 5-chloro-2-(chloromethyl)-1-(3-(methylsulfonyl)propyl)-1H-benzo[d]imidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09206191B2
Source datasetuspto-grants-2015_12
ORD IDord-c6ee63e9658b4570aee8b52d417eba96
Source noteuspto-grants-2015_12