HCID 118114327, compound → HCID 72950637, compound

HRID 1500872Notes

Reaction equation

HRID 1500872 reaction equation
[Cl:1][C:2]1[CH:18]=[CH:17][C:5]2[N:6]([CH:11]3[CH2:15][CH2:14][CH:13]([OH:16])[CH2:12]3)[C:7]([CH2:9]Cl)=[N:8][C:4]=2[CH:3]=1.[CH3:19][S:20]([C:23]1[C:31]2[C:26](=[CH:27][N+:28]([O-:32])=[CH:29][CH:30]=2)[NH:25][N:24]=1)(=[O:22])=[O:21].CS(C1C2C(=CN=CC=2)NN=1)(=O)=O>>[Cl:1][C:2]1[CH:18]=[CH:17][C:5]2[N:6]([CH:11]3[CH2:15][CH2:14][CH:13]([OH:16])[CH2:12]3)[C:7]([CH2:9][N:25]3[C:26]4=[CH:27][N+:28]([O-:32])=[CH:29][CH:30]=[C:31]4[C:23]([S:20]([CH3:19])(=[O:22])=[O:21])=[N:24]3)=[N:8][C:4]=2[CH:3]=1

Participants

4

Reactant 3

HCID 118114327HCID 118114327, compoundHCID 178504858HCID 178504858, compoundHCID 178504860HCID 178504860, compound

Product 1

HCID 72950637HCID 72950637, compound

Procedure

The title compound was prepared in analogy to Example 2-1 by using 3-(5-chloro-2-chloromethyl-benzoimidazol-1-yl)-cyclopentanol and 3-methanesulfonyl-1H-pyrazolo[3,4-c]pyridine 6-oxide instead of 5-chloro-2-chloromethyl-1-((S)-1,1-dioxo-tetrahydro-1λ6-thiophen-3-yl)-1H-benzoimidazole and 3-(methylsulfonyl)-1H-pyrazolo[3,4-c]pyridine.

Sources & evidence

ORD record
ord-7d0c701d1d0f479fb29e13d98e5f4e46
Source dataset
uspto-grants-2015_12
Patent number
US09206191B2

Reaction notes

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