HCID 118114302, compound → HCID 72950639, compound

HRID 1500874Notes

Reaction equation

HRID 1500874 reaction equation
C(OC([N:8]1[CH2:11][CH:10]([N:12]2[C:16]3[CH:17]=[CH:18][C:19]([Cl:21])=[CH:20][C:15]=3[N:14]=[C:13]2[CH2:22]Cl)[CH2:9]1)=O)(C)(C)C.[CH3:24][S:25]([C:28]1[C:36]2[C:31](=[CH:32][N:33]=[CH:34][CH:35]=2)[NH:30][N:29]=1)(=[O:27])=[O:26]>>[NH:8]1[CH2:9][CH:10]([N:12]2[C:16]3[CH:17]=[CH:18][C:19]([Cl:21])=[CH:20][C:15]=3[N:14]=[C:13]2[CH2:22][N:30]2[C:31]3=[CH:32][N:33]=[CH:34][CH:35]=[C:36]3[C:28]([S:25]([CH3:24])(=[O:26])=[O:27])=[N:29]2)[CH2:11]1

Participants

3

Reactant 2

HCID 118114302HCID 118114302, compoundHCID 178504858HCID 178504858, compound2×

Product 1

HCID 72950639HCID 72950639, compound

Procedure

The title compound was prepared in analogy to Example 2-13 by using 3-(5-chloro-2-chloromethyl-benzoimidazol-1-yl)-azetidine-1-carboxylic acid tert-butyl ester and 3-methanesulfonyl-1H-pyrazolo[3,4-c]pyridine instead of 3-(5-chloro-2-chloromethyl-benzoimidazol-1-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester and 3-methanesulfonyl-1H-pyrazolo[3,4-c]pyridine.

Sources & evidence

ORD record
ord-aa202b1604ae4e7fa22435c8d14a5742
Source dataset
uspto-grants-2015_12
Patent number
US09206191B2

Reaction notes

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