HCID 89923896, compound → HCID 72950816, compound

HRID 1500900Notes

Reaction equation

HRID 1500900 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[N:6]([CH2:11][CH2:12][CH2:13][C:14]([F:17])(F)F)[C:7]([CH2:9]Cl)=[N:8][C:4]=2[CH:3]=1.[CH3:20][S:21]([C:24]1[C:32]2[C:27](=[CH:28][N:29]=[CH:30][CH:31]=2)[NH:26][N:25]=1)(=[O:23])=[O:22].CS([C:37]1C2C(=CC=CC=2)N[N:38]=1)(=O)=O>>[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[N:6]([C:11]3[CH:37]=[N:38][C:14]([F:17])=[CH:13][CH:12]=3)[C:7]([CH2:9][N:26]3[C:27]4=[CH:28][N:29]=[CH:30][CH:31]=[C:32]4[C:24]([S:21]([CH3:20])(=[O:23])=[O:22])=[N:25]3)=[N:8][C:4]=2[CH:3]=1

Participants

4

Reactant 3

HCID 89923896HCID 89923896, compoundHCID 1785048563-methanesulfonyl-1H-indazoleHCID 178504858HCID 178504858, compound

Product 1

HCID 72950816HCID 72950816, compound

Procedure

The title compound was prepared in analogy to Example 3-1 by using 5-chloro-2-chloromethyl-1-(4,4,4-trifluoro-butyl)-1H-benzoimidazole and 3-methanesulfonyl 1H-pyrazolo[3,4-c]pyridine instead of 5-chloro-2-chloromethyl-1-(4,4,4-trifluoro-butyl)-1H-benzoimidazole and 3-methanesulfonyl-1H-indazole.

Sources & evidence

ORD record
ord-361650fe66be40ea88fa03711f59c27e
Source dataset
uspto-grants-2015_12
Patent number
US09206191B2

Reaction notes

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