HCID 89924297, compound → HCID 72948353, compound

HRID 1500909Notes

Reaction equation

HRID 1500909 reaction equation
[Cl:1][C:2]1[CH:19]=[C:18]([F:20])[C:5]2[N:6]([CH2:11][CH2:12][CH2:13][C:14]([F:17])([F:16])[F:15])[C:7]([CH2:9]Cl)=[N:8][C:4]=2[CH:3]=1.ClC1C=C(F)C2N(CCC(F)(F)F)C(CCl)=NC=2C=1.[CH3:40][S:41]([C:44]1[C:52]2[C:47](=[CH:48][N:49]=[CH:50][CH:51]=2)[NH:46][N:45]=1)(=[O:43])=[O:42].CS(C1C2C(=CN=CC=2)NN=1)(=O)=O>>[Cl:1][C:2]1[CH:19]=[C:18]([F:20])[C:5]2[N:6]([CH2:11][CH2:12][CH2:13][C:14]([F:17])([F:16])[F:15])[C:7]([CH2:9][N:46]3[C:47]4=[CH:48][N:49]=[CH:50][CH:51]=[C:52]4[C:44]([S:41]([CH3:40])(=[O:42])=[O:43])=[N:45]3)=[N:8][C:4]=2[CH:3]=1

Participants

4

Reactant 3

HCID 89924297HCID 89924297, compoundHCID 178504858HCID 178504858, compoundHCID 178504859HCID 178504859, compound

Product 1

HCID 72948353HCID 72948353, compound

Procedure

The title compound was prepared in analogy to Example 5-1 by using 5-chloro-2-(chloromethyl)-7-fluoro-1-(4,4,4-trifluorobutyl)-1H-benzo[d]imidazole and 3-(methylsulfonyl)-1H-pyrazolo[3,4-c]pyridine 5-chloro-2-(chloromethyl)-7-fluoro-1-(3,3,3-trifluoropropyl)-1H-benzo[d]imidazole and 3-(methylsulfonyl)-1H-pyrazolo[3,4-c]pyridine.

Sources & evidence

ORD record
ord-fd84a649f795450d9edb1fd178cdb050
Source dataset
uspto-grants-2015_12
Patent number
US09206191B2

Reaction notes

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