HCID 89933234, compound → HCID 72949630, compound

HRID 1500945Notes

Reaction equation

HRID 1500945 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[C:5]([NH:11][C@@H:12]2[CH2:16][CH2:15][S:14](=[O:18])(=[O:17])[CH2:13]2)=[C:4]([F:19])[CH:3]=1.[CH3:20][S:21]([C:24]1[C:32]2[C:27](=[CH:28][N:29]=[CH:30][CH:31]=2)[NH:26][N:25]=1)(=[O:23])=[O:22].CS([C:37]1[C:45]2C(=CC=CC=2)NN=1)(=O)=O>>[Cl:1][C:2]1[CH:3]=[C:4]([F:19])[C:5]2[N:11]([C@@H:12]3[CH2:16][CH2:15][S:14](=[O:18])(=[O:17])[CH2:13]3)[C:37]([CH2:45][N:26]3[C:27]4=[CH:28][N:29]=[CH:30][CH:31]=[C:32]4[C:24]([S:21]([CH3:20])(=[O:23])=[O:22])=[N:25]3)=[N:8][C:6]=2[CH:7]=1

Participants

4

Reactant 3

HCID 89933234HCID 89933234, compoundHCID 1785048563-methanesulfonyl-1H-indazoleHCID 178504858HCID 178504858, compound

Product 1

HCID 72949630HCID 72949630, compound

Procedure

The title compound was prepared in analogy to Example 2-1 by using (4-chloro-2-fluoro-6-nitrophenyl)-((R)-1,1-dioxo-tetrahydro-1λ6-thiophen-3-yl)-amine and 3-(methylsulfonyl)-1H-pyrazolo[3,4-c]pyridine instead of (4-chloro-2-nitro-phenyl)-((R)-1,1-dioxo-tetrahydro-1λ6-thiophen-3-yl)-amine and 3-methanesulfonyl-1H-indazole.

Sources & evidence

ORD record
ord-ec4dc6683d2143ad922211819ac261f8
Source dataset
uspto-grants-2015_12
Patent number
US09206191B2

Reaction notes

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