HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylethyl 4-(1-phenylethyl)benzoate → 4-(1-Phenylethyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylethyl 4-(1-phenylethyl)benzoate | HCID 89580568 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 4-(1-Phenylethyl)benzoic acid | HCID 19599974 | 90% |
Reaction Steps
To a solution of tert-butyl 4-(1-phenylethyl)benzoate (500 mg, 1.77 mmol) in dichloromethane (8 mL), trifluoroacetic acid (2 mL) was added. The mixture was stirred for 0.5 hour. Once the start material was consumed, the resultant mixture was concentrated to give 4-(1-phenylethyl)benzoic acid (360 mg, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09206128B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-e142941996744b62bb906ae28c777d89 |
| Source note | uspto-grants-2015_12 |