Trifluoroacetic acid → HCID 89581161, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of tert-butyl 4-(methoxy(phenyl)methyl)benzoate (200 mg, 0.67 mmol), 2,2,2-trifluoroacetic acid (1 mL) and dichloromethane (4 mL) were stirred at 20° C. for 4 hours. The mixture was concentrated to give a residue. The residue was purified by column chromatography (silica gel, petroleum ether/ethyl acetate=2:1) to give 4-(methoxy(phenyl)methyl)benzoic acid as a white solid (162 mg, 100%).

Provenance & Evidence