HCID 89580481, compound → HCID 89580875, compound

HRID 1501177Notes

Reaction equation

HRID 1501177 reaction equation
[C:1]1([C:6]2[CH:18]=[CH:17][C:9]([C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])=[CH:8][CH:7]=2)[CH2:5][CH2:4][CH2:3][CH:2]=1>CO.[Pd]>[CH:1]1([C:6]2[CH:7]=[CH:8][C:9]([C:10]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:11])=[CH:17][CH:18]=2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

4

Reactant 1

HCID 89580481HCID 89580481, compound

Product 1

HCID 89580875HCID 89580875, compoundYield 86.6%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

To a solution of tert-butyl 4-cyclopentenylbenzoate (400 mg, 1.64 mmol) in methanol (20 mL) was added palladium on carbon (10%, 100 mg). The mixture was stirred for 24 hours at room temperature under hydrogen atmosphere. The mixture was filtered and concentrated in vacuo to give tert-butyl 4-cyclopentylbenzoate (350 mg, 86%) as a white solid. LRMS (M+H+) m/z: calcd 246.16. found 246

Workup

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-7f6c82dd4d8c4d57846b8c7a6a9802a6
Source dataset
uspto-grants-2015_12
Patent number
US09206128B2

Reaction notes

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