Dimethylformamide dimethyl acetal → 1-(3-Cyanophenyl)-3-(dimethylamino)acrolein

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

3-Acetylbenzonitrile (0.435 g, 0.00300 mol) and 1,1-dimethoxy-N,N-dimethylmethanamine (0.400 mL, 0.00301 mol) were combined and heated in sealed tube to 120° C. in the microwave for 15 min. The reaction was then allowed to cool to rt giving the 3-[(2E)-3-(dimethylamino)prop-2-enoyl]-benzonitrile as a red-orange crystalline material, LC/MS (M+H)+: 201.

Herkunft & Nachweise