HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1501775Generated: November 2, 2026
Hydrogen Bromide → 4-hydroxy-3-isopropylfuran-2(5H)-one
https://huagongshe.com/reaction/1501775
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | HCID 86709464 | HCID 86709464 | — |
| Product | 4-hydroxy-3-isopropylfuran-2(5H)-one | HCID 58980287 | — |
Reaction Steps
A mixture of ethyl 4-bromo-2-isopropyl-3-oxobutanoate (7.1 g, 28 mmol) and hydrogen bromide (48%, 0.032 mL, 0.28 mmol) was heated at 100° C. for 8 h. After cooling to rt, the solid was collected by filtration followed by diethyl ether washing to give 4-hydroxy-3-isopropylfuran-2(5H)-one. LCMS: (M+1)+:143.09.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09206198B2 |
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| Source dataset | uspto-grants-2015_12 |
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| ORD ID | ord-38e49f77a07d4c18ba9fbbce38fa0e3b |
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| Source note | uspto-grants-2015_12 |
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