反应详情

A mixture of 5-bromo-4-vinyl-2-benzofuran-1(3H)-one (2.0 g, 8.37 mmol) and PdC (400 mg) in 50 mL of MeOH was stirred at rt. under H2 (1 atm) overnight, and then filtered. The filtrate was concentrated. The resulting oil was purified by column chromatography to give 5-bromo-4-ethyl-2-benzofuran-1(3H)-one.

1. filtrationunder H2 (1 atm) overnight, and then filtered
2. concentrationThe filtrate was concentrated
3. customThe resulting oil was purified by column chromatography