HCID 131734286, compound → HCID 131734285, compound

HRID 1501923Notes

Reaction equation

HRID 1501923 reaction equation
[B:1]([OH:28])([OH:27])[C@@H:2]([NH:7][C:8]([C@@H:10]([NH:18][C:19]([C:21]1[CH:22]=[N:23][CH:24]=[CH:25][N:26]=1)=[O:20])[CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:9])[CH2:3][CH:4]([CH3:6])[CH3:5].[C:29]([C@H:32]([C@@H:34]([C:36]([O-:38])=[O:37])[OH:35])[OH:33])([O-:31])=[O:30]>CS(C)=O>[B:1]([OH:28])([OH:27])[C@@H:2]([NH:7][C:8]([C@@H:10]([NH:18][C:19]([C:21]1[CH:22]=[N:23][CH:24]=[CH:25][N:26]=1)=[O:20])[CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9])[CH2:3][CH:4]([CH3:6])[CH3:5].[C:29]([CH:32]([CH:34]([C:36]([O-:38])=[O:37])[OH:35])[OH:33])([O-:31])=[O:30]

Participants

3

Reactant 1

HCID 131734286HCID 131734286, compound

Product 1

HCID 131734285HCID 131734285, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent2×

Procedure

3.8 g (5+5) bis-bortezomib tartrate III, prepared as described in example 2, were dissolved in 100 ml DMSO (mother solution). An aliquot of 1 ml of such solution was diluted with 1 ml DMSO.

Sources & evidence

ORD record
ord-83f511ab548c454192274d47863dd078
Source dataset
uspto-grants-2015_12
Patent number
US09206229B2

Reaction notes

Loading…