反应详情

The mixture of Benzyl 9a-methyl-3-((S)-3-methyl-1-oxoisochroman-6-yl)hexahydropyrazino[2,1-c][1,4]oxazine-8(1H)-carboxylate (215 mg, 0.500 mmol) and 10% Pd—C (56 mg, 0.05 mmol) in MeOH (10 mL) was stirred under a hydrogen balloon for 16 h. After which point, the solution was filtered through Celite and the resulting filtrate was concentrated to afford the title compound: LC/MS: m/e 317.2 (M+H)+.

1. filtrationAfter which point, the solution was filtered through Celite
2. concentrationthe resulting filtrate was concentrated