HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(6-methyl-5-nitropyridin-2-YL)acetate → Ethyl 2-(5-amino-6-methyl-2-pyridinyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(6-methyl-5-nitropyridin-2-YL)acetate | HCID 53419421 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Ethyl 2-(5-amino-6-methyl-2-pyridinyl)acetate | HCID 89619013 | — |
Reaction Steps
Ethyl 2-(6-methyl-5-nitropyridin-2-yl)acetate (1.10 g, 4.91 mmol) was dissolved in ethyl acetate and added Pd/C (0.5 g) then stirred under a balloon of hydrogen for 2 hrs. Filtered over catalyst and concentrated to yield ethyl 2-(5-amino-6-methylpyridin-2-yl)acetate: LC-MS: M+1=195;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09206199B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-87e45446156942d5bebbfb531899a8d7 |
| Source note | uspto-grants-2015_12 |