Dimethylformamide → HCID 131734302, compound

Participants

Reaction Steps

2,7-Dibromo-N-(4-hydroxyphenyl)carbazole (1.24 g) and 60% sodium hydride (0.11 g) were added at 0° C. to N,N-dimethylformamide (DMF) (40 mL), followed by stirring for 1 hour. Then, 8-bromooctanol (0.65 g) was added thereto, and the mixture was stirred at room temperature for 3 hours and at 50° C. for 2 hours. The resultant mixture was extracted with ethyl acetate, washed with water and dried. The crude product was treated through silica gel column chromatography (eluent: 25% ethyl acetate/toluene solution), to thereby obtain 1.30 g of 2,7-dibromo-N-4-[(8-hydroxyoctyloxyphenyl]carbazole as colorless viscous liquid.

Provenance & Evidence