HRID1502453

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10265223

2-chloro-3-fluoro-5-iodo-4-methylpyridine

C6H4ClFIN

结构：CC1(C)OB(c2ccc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c2)OC1(C)C

HCID71115194

未命名化合物

PRODUCTS

生成物

结构：Cc1c(-c2ccc3cc(NC(=O)[C@@H]4C[C@@H]4F)ncc3c2)cnc(Cl)c1F

HCID86674978

未命名化合物

PROCEDURE

实验过程

The title compound was prepared following a procedure similar to that described for Example 12, using 2-chloro-3-fluoro-5-iodo-4-methyl-pyridine and (1S,2S)-2-fluoro-N-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoquinolin-3-yl)cyclopropanecarboxamide, and was carried forward without purification; 0.407 g (98%).

WORKUP

后处理

customwas carried forward without purification