Hydrochloric Acid → Sodium hydroxide rebamipide

Participants

Reaction Steps

373 ML of 10 N hydrochloric acid (440 g, 3.73 mol) and 14.8 L of an aqueous solution containing 4% (w/v) HPMC (TC-5E) were mixed to prepare a hydrochloric acid-HPMC ITC-5E) solution. To 14 L of an aqueous solution of sodium hydroxide which was prepared by adding purified water to 134 g of sodium hydroxide (3.35 mol), 600 g of rebamipide (1.62 mol) was added and dissolved with heating to give a sodium hydroxide-rebamipide solution.

Provenance & Evidence