Hydrochloric Acid → Sodium hydroxide rebamipide

Participants

Reaction Steps

183 ML of 10 N hydrochloric acid (216 g, 1.83 mol) and 3.9 L of an aqueous solution containing 7.67% (w/v) HPMC (TC-5E) were mixed to prepare a hydrochloric acid-HPMC (TC-5E) solution. To 10.5 L of an aqueous solution of sodium hydroxide which was prepared by adding purified water to 66 g of sodium hydroxide (1.65 mol), 300 g of rebamipide (0.81 mol) was added and dissolved with heating to give a sodium hydroxide-rebamipide solution.

Provenance & Evidence