Zinc acetate (USP) → HCID 136341386, compound

Participants

Reaction Conditions

Reaction Steps

A porphyrin 5a (266 mg, 0.200 mmol) was dissolved in anhydrous chloroform, and the mixture was stirred at 70° C. for 45 min under a nitrogen atmosphere. To the mixture was added zinc acetate dihydrate (439 mg, 2.00 mmol) dissolved in anhydrous methanol (4 mL), and the mixture was stirred at 70° C. for 4 hours. The mixture was cooled to room temperature, concentrated and then washed with water. The mixture was dried over sodium sulfate and concentrated. The residual material was purified by silica gel column chromatography [methylene chloride/hexane (2:1)], to give compound 6a (purple-red solid) (yield: 272 mg, 98%).

Provenance & Evidence