HCID 117702502, compound → HCID 117717162, compound

Participants

Reaction Steps

To a stirred solution of tert-butyl 3-(hydroxymethyl)-1-adamantylcarbamate (1.2 g, 4.3 mmol) in DCM (50 mL) was added PCC (1.4 g, 6.5 mmol) in portions under N2 atmosphere. After stirring at room temperature for two hours. the mixture was filtered through a pad of silica gel and the filtrate was concentrated under reduced pressure to give 1.1 g (92%) of the title compound, tert-butyl-3-formyl-1-adamantylcarbamate, as a brown oil, which was used in the next step without further purification. ESI-MS m/z: 224 (M-55)+.

Provenance & Evidence