HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-methyl-2-butenoate → HCID 90010720, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-methyl-2-butenoate | HCID 13546 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | HCID 178434564 | HCID 178434564 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 90010720 | HCID 90010720 | 7% |
Reaction Steps
A solution of 3-methyl-4-nitro-1H-pyrazole (1.00 g, 7.87 mmol), methyl 3-methylbut-2-enoate (2.20 g, 18.9 mmol), and DBU (3.10 g, 20.5 mmol) in DMF (5.0 mL) was stirred overnight. The mixture was purified by reverse phase Combiflash to afford the title compound (130 mg, 7%) as yellow oil. LC-MS (ESI): m/z=242 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09212173B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-9eca3424a24a4b7a9e76b1bbfdc092cf |
| Source note | uspto-grants-2015_12 |