反应详情

温度

130 °C

A suspension of compound 2 (180 mg, 0.4 mmol) and Lawesson's Reagent (180 mg, 0.44 mmol) in dry toluene (4 mL) was heated under 130° C. for 35 min in a CEM microwave reactor. The mixture was concentrated in vacuo and the residue was purified by column (eluent:petroleum ether:ethyl acetate=5:1) to give compound 3 as a white solid (96 mg, 50%) as a white solid.

1. concentrationThe mixture was concentrated in vacuo
2. customthe residue was purified by column (eluent:petroleum ether:ethyl acetate=5:1)