反应详情

To solution of compound 5 (100 mg, 0.26 mmol) and Lawesson'reagent (104 mg, 0.26 mmol) in dioxane (3 mL) was heated at 150° C. for 30 min in a microwave reactor. The mixture was cooled, and concentrated in vacuo. The residue was purified by column chromatography on silica gel (hexanes:EtOAc=20:1) to give compound 7 (30 mg, 38%) as a light orange solid.

1. temperatureThe mixture was cooled
2. concentrationconcentrated in vacuo
3. customThe residue was purified by column chromatography on silica gel (hexanes:EtOAc=20:1)