Phosphorus tribromide → HCID 86715430, compound

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Reaction Steps

The compound was prepared according to general procedure G with ethyl 2-(2-chloro-4-(hydroxymethyl)-6-methoxyphenoxy)acetate (1.3 mmol) in dichloromethane (12 ml) and PBr3 (1.3 mmol). 338 mg of compound were obtained (78% yield). This compound was used without further purification. 1H NMR (250 MHz, CD3OD): δ 1.29 (m, 3H), 3.83 (s, 3H), 4.15 (m, 2H), 4.55 (s, 2H), 4.94 (s, 2H) 6.80 (d, J=2.0 Hz, 1H), 6.85 (d, J=2.0 Hz, 1H). MS (ESI): m/z 336.9 [M−H]−, 360.8 [M+Na]+

Provenance & Evidence