HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Alcohol → 4-[1-(4-fluorophenyl)ethoxy]-1-{4-[2-(1-pyrrolidinyl)ethoxy]phenyl}-1H-pyridin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Alcohol | HCID 244 | — |
| Reactant | 1-(4-Fluorophenyl)ethanol | HCID 73946 | — |
| Reactant | 4-Benzyloxy-2(1H)-pyridone | HCID 3607724 | — |
| Reactant | 4-benzyloxy-1-{5-[2-(1-piperidinyl)ethoxy]pyridin-2-yl}-1H-pyridin-2-one | HCID 58964920 | — |
| Reactant | 4-[1-(4-fluorophenyl)ethoxy]-1H-pyridin-2-one | HCID 68431172 | — |
| Product | 4-[1-(4-fluorophenyl)ethoxy]-1-{4-[2-(1-pyrrolidinyl)ethoxy]phenyl}-1H-pyridin-2-one | HCID 58964990 | — |
Reaction Steps
Example 12 was repeated except that 4-[1-(4-fluorophenyl)ethoxy]-1H-pyridin-2-one as obtained by repeating Steps (1) and (2) of Example 1 in which benzyl alcohol was replaced with 1-(4-fluorophenyl)ethanol, was used in place of 4-benzyloxy-1H-pyridin-2-one, to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732456B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-f4d25164b2b74b7ebebb66f4dc242b34 |
| Source note | uspto-grants-2010_06 |